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Microbial Production of N-Acetylglucosamine


N-acetylglucosamine (NAG) is an amino sugar that is an important constituent of many natural polysaccharides. N-acetylglucosamine is also a valuable pharmacological product and an important component of protein synthesis which has a positive effect on tissue regeneration in the animal and human body. N-acetylglucosamine is currently produced by the acetylation of glucosamine, a product of the acid hydrolysis of chitin. That process is limited by poor yields and the availability of raw materials such as crab shells. To overcome these limitations, strains of E. coli have been developed at BTR for the commercial production of N-acetylglucosamine by fermentation.



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Tom Jerrell, President
Bio-Technical Resources
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