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BTR's Capabilities and Equipment

Fermentation Equipment

• 36 one-liter fermentors
• 6 three-liter fermentors
• 12 14-liter fermentors
• 4 60-liter fermentors
• 1 250-liter fermentor
• 1 300-ml pressure reactor
• Off-gas analysis
• Digital data acquisition

Analytical Equipment

• HPLC units with Waters Empower 2 Data Management
• GC/MS
• IC
• Mettler automated titrators
• UV/VIS scanning spectrophotometers
• Microplate reader/scanning UV
• Cooled CCD camera imaging system

Product Recovery Capabilities/Equipment

• Continuous centrifuges
• Ultrafiltration devices
• Rotary vacuum filter (lab/pilot scale)
• Homogenizer for cell disruption
• Pharmacia FPLC systems
• Pilot-scale chromatography columns for custom applications
• Crystallization (lab scale)
• Extraction (lab scale)
• Vacuum evaporation
• Spray dryer

Microbiology and Biochemistry Equipment

• Anaerobic chambers (for anaerobic microorganism culturing)
• Constant temperature shakers
• Constant temperature rooms
• Incubators
• Biohazard safety cabinets
• Laminar flow hood
• Autoclaves
• Centrifuges
• Ovens
• Water baths
• Liquid handling system
• Lyophilizer
• Microscopes (Phase Contrast, Bright Field, DIC, Fluorescence)
• French Press
• Sonicator

Molecular Biology Equipment

• Electrophoresis (SDS PAGE, Agarose Gels, Southern Blots, Western Blots)
• PCR
• Electroporation
• Hybridization chambers
• UV crosslinker

Radioactive Materials License for ¹⁴C, ³H, ³²P, ³³P, ³⁵S

• Radioisotope rooms
• Scintillation counter
• Phosphor imaging system